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More than 60 epidemiology studies conducted over the last 20 years have shown that Vitamin D deficiency is associated with increased rates of cancer. (8) A placebo controlled study has confirmed these findings. In the study, vitamin D supplements reduced the incidence of cancer by as much as 77% compared to patients who were given placebo (sugar pill).(29) (See worldside reaction to these data) The incidence of cancer is reduced by 17% and the death rate from cancer by 29% for every 10ng/ml increase in the blood level of vitamin D. The effect is particularly strong for cancers of the gastrointestinal tract where the reduction in death rate was 45% for the same increase in plasma levels of vitamin D. (30) Two clinical trials have demonstrated that the higher the blood level of vitamin D, the greater the degree of protection against developing cancer. (29) High vitamin D levels (based on latitude and UV exposure) also correlate with a decreased risk of developing lung cancer, a 45% and 65% reduction in men and women respectively. Similar effects have been demonstrated in colon, prostate, renal and endometrial cancer. (33) For more information on Vitamin D in the prevention of particular types of cancer, see our information site www.vitaminD3world.com
For each 10ng/ml increase in the blood level of vitamin D, the death rate from cancer would be reduced by 29%. The relationship between vitamin D and colorectal cancer is particularly strong. The death rate for colorectal cancer would be reduced by 49% (30) A Norwegian study showed that cancer patients diagnosed in the summer when vitamin D levels are highest had up to 40% better survival rates than patients diagnosed in the winter when vitamin D levels are at their lowest. (56) Breast cancer patients with low levels of vitamin D followed over eleven years had a 70% greater chance of dying and twice the rate of developing metastasis than patients with high levels of vitamin D.(90) Early stage lung cancer patients who were diagnosed in the summer and had the highest levels of vitamin D had a five-year survival of 73% compared to 30% for those diagnosed in the winter with low vitamin D levels. (60) The risk of death for colorectal cancer patients with advanced disease but with high levels of vitamin D was reduced by over 60% compared to patients with low vitamin D levels. (64) Prostate Cancer Patients with Vitamin D levels in the mid and high range had a 60% and 85% respectively reduced risk of death from the condition compared to patients with low levels of Vitamin D. This is almost a seven fold increase in the risk of death in those with low vis high vitamin D levels.(152) For more information on Vitamin D in the treatment of particular types of cancer, see our information site www.vitaminD3world.com
Multiple Sclerosis (MS) is more common in Northern parts of the world which have less sunlight. (106) Studies have shown that the risk of MS is decreased by exposure to sunlight in childhood. (106) Epidemiology data suggests that Vitamin D deficiency in the last three months of pregnancy is particularly harmful to the fetus and raises the risk of MS in later life. (111) Nurses who took 400IU per day of Vitamin D as part of a multivitamin demonstrated a 40% reduced risk of developing MS. (107) Professor Ebers of Oxford University has shown that vitamin D interacts with a specific region of a gene, which is known to exert a direct influence on the risk of developing MS. (118)
Only 16% of MS patient experienced a relapse when treated with 14,000IU per day of Vitamin D for twelve months compared to 40% of patients treated with only 1000IU. (American Academy of Neurology April 2009)Nee follow up on this)
For every 10ng increase in Vitamin D level, 32% less brains lesions were detected by MRI in MS patients (176) Each 4 nanogram increase in Vitamin D level reduced relapse rate in MS patients by 13.7 % (177) For more information on Vitamin D in Multiple Sclerosis please see our information site www.vitaminD3world.com
Low levels of Vitamin D are associated with increasing severity of asthma in children. (171) Asthamtic children with low Vitamin D levels use more inhaled steroids and experience more hospitalizations than those with higher levels. (171) Decreased lung function is shown to correlate with low Vitamin D levels in adult asthmatics. (173) Asthmatic patients with low vitamin D levels do not respond to corticosteroids as well as those with higher vitamin D levels .(173) The action of steroids on inflammatory cells taken from patients with asthma were enhanced tenfold by the presence of Vitamin D. (174) Children taking Vitamin D supplements had a six-fold reduction in the number of asthma attacks compared to those on placebo. (175)